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Phenolic Compounds in Agro-Industrial Waste of Mango Fruit: Impact on Health and Its Prebiotic Effect – a Review
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Tecnológico Nacional de México/Tecnológico de Estudios Superiores de San Felipe del Progreso. División de Ingeniería en Industrias Alimentarias. Av. Instituto Tecnológico, S/N, ejido de San Felipe del Progreso, 50640, San Felipe del Progreso, Estado de México, México
Tecnológico Nacional de México/Tecnológico de Estudios Superiores de San Felipe del Progreso. División de Ingeniería en Energías Renovables. Av. Instituto Tecnológico, S/N, ejido de San Felipe del Progreso, 50640, San Felipe del Progreso, Estado de México, México
IPICYT, Instituto Potosino de Investigación Científica y Tecnológica A.C., Camino a La Presa San José 2055, Col. Lomas 4a Sección, San Luis Potosí, SLP, 78216, México
Jorge Luis González Escobar   

Ingeniería en Industrias Alimentarias, Tecnológico Nacional de México/Tecnológico de Estudios Superiores de San Felipe del Progreso, Av. Instituto Tecnológico, 50640, San Felipe del Progreso, Mexico
Submission date: 2022-11-26
Acceptance date: 2023-01-16
Online publication date: 2023-02-21
Publication date: 2023-02-21
Pol. J. Food Nutr. Sci. 2023;73(1):5–23
The fruit processing industry generates huge amounts of waste annually, causing severe environmental problems. Mango processing produces around 20 million tons of wastes from the non-consumed fraction, mainly peels and seeds, which constitute 30–60% of the fruit weight. However, various phytochemicals found in these residues have been implicated in preventing cancer and also cardio-metabolic and gastrointestinal diseases. Particularly, phenolic compounds hold a promising potential to be utilized as modulatory agents of the human gut microbiota (prebiotics-like actions). This review article mainly discusses the effect of phenolics from mango wastes on gut microbiota modulation and its beneficial repercussions for human health. Moreover, it also discusses the importance of phenolic compounds of mango peel and seed kernel residues, their extraction, identification, and quantification.
This study was supported by the Cátedras COMECyT-EDOMEX program of the Consejo Mexiquense de Ciencia y Tecnología del Estado de México, Mexico provided to Mayra Nicolás García (CAT2021-0048).
This study received no external funding.
The authors of the manuscript declare that they have no conflict of interest.
Abbasi, A.M., Liu, F., Guo, X., Fu, X., Li, T., Liu, R.H. (2017). Phytochemical composition, cellular antioxidant capacity and antiproliferative activity in mango (Mangifera indica L.) pulp and peel. International Journal of Food Science and Technology, 52(3), 817–826.
Abdel-Aty, A.M., Salama, W.H., Hamed, M.B., Fahmy, A.S., Mohamed, S.A. (2018). Phenolic-antioxidant capacity of mango seed kernels: therapeutic effect against viper venoms. Revista Brasileira de Farmacognosia, 28(5), 594–601.
Alañón, M.E., Pimentel-Moral, S., Arráez-Román, D., Segura-Carretero, A. (2021a). Profiling phenolic compounds in underutilized mango peel by-products from cultivars grown in Spanish subtropical climate over maturation course. Food Research International, 140, art. no. 109852.
Alañón, M.E., Pimentel-Moral, S., Arráez-Román, D., Segura-Carretero, A. (2021b). HPLC-DAD-Q-ToF-MS profiling of phenolic compounds from mango (Mangifera indica L.) seed kernel of different cultivars and maturation stages as a preliminary approach to determine functional and nutraceutical value. Food Chemistry, 337, art. no. 127764.
Anaya-Loyola, M.A., García-Marín, G., García-Gutiérrez, D.G., Castaño-Tostado, E., Reynoso-Camacho, R., López-Ramos, J.E., Enciso-Moreno, J.A., Pérez-Ramírez, I.F. (2020). A mango (Mangifera indica L.) juice by-product reduces gastrointestinal and upper respiratory tract infection symptoms in children. Food Research International, 136, art. no. 109492.
Anzoise, M.L., Basso, A.R., Del Mauro, J.S., Carranza, A., Ordieres, G.L., Gorzalczany, S. (2018). Potential usefulness of methyl gallate in the treatment of experimental colitis. Inflammopharmacology, 26(3), 839–849.
Asif, A., Farooq, U., Akram, K., Hayat, Z., Shafi, A., Sarfraz, F., Sidhu, M.A.I., Rehman, H.U., Aftab, S. (2016). Therapeutic potentials of bioactive compounds from mango fruit wastes. Trends in Food Science and Technology, 53, 102–112.
Azhar, A., Aamir, K., Asad, F., Kazi, H.A., Farooqui, M.U. (2019). Therapeutic effect of mango seed extract in diabetes mellitus. The Professional Medical Journal, 26(09), 1551–1556.
Ballesteros-Vivas, D., Álvarez-Rivera, G., Morantes, S.J., Sánchez-Camargo, A.P., Ibáñez, E., Parada-Alfonso, F., Cifuentes, A. (2019a). An integrated approach for the valorization of mango seed kernel: Efficient extraction solvent selection, phytochemical profiling and antiproliferative activity assessment. Food Research International, 126, art. no. 108616.
Ballesteros-Vivas, D., Alvarez-Rivera, G., Ocampo, A.F.G., Morantes, S.J., Sánchez-Camargo, A.P., Cifuentes, A., Parada-Alfonso, F., Ibáñez, E. (2019b). Supercritical antisolvent fractionation as a tool for enhancing antiproliferative activity of mango seed kernel extracts against colon cancer cells. The Journal of Supercritical Fluids, 152, art. no. 104563.
Bento-Silva, A., Koistinen, V.M., Mena, P., Bronze, M.R., Hanhineva, K., Sahlstrøm, S., Kitrytė, V., Moco, S., Aura, A.-M. (2020). Factors affecting intake, metabolism and health benefits of phenolic acids: do we understand individual variability? European Journal of Nutrition, 59(4), 1275–1293.
Blancas-Benitez, F.J., Mercado-Mercado, G., Quirós-Sauceda, A.E., Montalvo-González, E., González-Aguilar, G.A., Sáyago-Ayerdi, S.G. (2015). Bioaccessibility of polyphenols associated with dietary fiber and in vitro kinetics release of polyphenols in Mexican ‘Ataulfo’ mango (Mangifera indica L.) by-products. Food and Function, 6(3), 859–868.
Borrás-Enríquez, A.J., Reyes-Ventura, E., Villanueva-Rodríguez, S.J., Moreno-Vilet, L. (2021). Effect of ultrasound-assisted extraction parameters on total polyphenols and its antioxidant activity from mango residues (Mangifera indica L. var. Manililla). Separations, 8(7), art. no. 94.
Buelvas-Puello, L.M., Franco-Arnedo, G., Martínez-Correa, H.A., Ballesteros-Vivas, D., Sánchez-Camargo, A.P., Miranda-Lasprilla, D., Narváez-Cuenca, C.-E., Parada-Alfonso, F. (2021). Supercritical fluid extraction of phenolic compounds from mango (Mangifera indica L.) seed kernels and their application as an antioxidant in an edible oil. Molecules, 26(24), art. no. 7516.
Cádiz-Gurrea, M.L., Villegas-Aguilar, M.C., Leyva-Jiménez, F.J., Pimentel-Moral, S., Fernández-Ochoa, Á., Alañón, M.E., Segura-Carretero, A. (2020). Revalorization of bioactive compounds from tropical fruit by-products and industrial applications by means of sustainable approaches. Food Research International, 138, art. no. 109786.
Castañeda-Valbuena, D., Ayora-Talavera, T., Luján-Hidalgo, C., Álvarez-Gutiérrez, P., Martínez-Galero, N., Meza-Gordillo, R. (2021). Ultrasound extraction conditions effect on antioxidant capacity of mango by-product extracts. Food and Bioproducts Processing, 127, 212–224.
Castro-Vargas, H.I., Ballesteros Vivas, D., Ortega Barbosa, J., Morantes Medina, S.J., Aristizabal Gutiérrez, F., Parada-Alfonso, F. (2019). Bioactive phenolic compounds from the agroindustrial waste of Colombian mango cultivars ‘sugar mango’ and ‘Tommy Atkins’—An alternative for their use and valorization. Antioxidants, 8(2), art. no. 41.
Coman, V., Vodnar, D.C. (2020). Hydroxycinnamic acids and human health: Recent advances. Journal of the Science of Food and Agriculture, 100(2), 483–499.
Das, P.C., Khan, M.J., Rahman, M.S., Majumder, S., Islam, M.N. (2019). Comparison of the physico-chemical and functional properties of mango kernel flour with wheat flour and development of mango kernel flour based composite cakes. NFS Journal, 17, 1–7.
De Ancos, B., Sánchez-Moreno, C., Zacarías, L., Rodrigo, M.J., Ayerdí, S.S., Benítez, F.J.B., Domínguez-Avila, J.A., González-Aguilar, G.A. (2018). Effects of two different drying methods (freeze-drying and hot air-drying) on the phenolic and carotenoid profile of ‘Ataulfo’ mango by-products. Journal of Food Measurement and Characterization, 12(3), 2145–2157.
Ediriweera, M.K., Tennekoon, K.H., Samarakoon, S.R. (2017). A review on ethnopharmacological applications, pharmacological activities, and bioactive compounds of Mangifera indica (Mango). Evidence-Based Complementary and Alternative Medicine, 2017, art. no. 6949835.
El-Kady, T.M.A., El-Rahman, M.K.A., Toliba, A.O., Abo El-maty, S.M. (2017). Evaluation of mango seed kernel extract as natural occurring phenolic rich antioxidant compound. Bulletin of the National Nutrition Institute of the Arab Republic of Egypt, 48(1), 1–30.
Fang, C., Kim, H., Barnes, R.C., Talcott, S.T., Mertens‐Talcott, S.U. (2018). Obesity‐associated diseases biomarkers are differently modulated in lean and obese individuals and inversely correlated to plasma polyphenolic metabolites after 6 weeks of mango (Mangifera indica L.) consumption. Molecular Nutrition and Food Research, 62(14), art. no. 1800129.
FAO (2020). Major tropical fruits – Preliminary market results 2019. Food and Agriculture Organization of the United Nations, Rome, Italy.
Fernández-Ochoa, Á., Cázares-Camacho, R., Borrás-Linares, I., Domínguez-Avila, J.A., Segura-Carretero, A., González-Aguilar, G.A. (2020). Evaluation of metabolic changes in liver and serum of streptozotocin-induced diabetic rats after Mango diet supplementation. Journal of Functional Foods, 64, art. no. 103695.
Gómez‐Caravaca, A.M., López‐Cobo, A., Verardo, V., Segura‐Carretero, A., Fernández‐Gutiérrez, A. (2016). HPLC‐DAD‐q‐TOF‐MS as a powerful platform for the determination of phenolic and other polar compounds in the edible part of mango and its by‐products (peel, seed, and seed husk). Electrophoresis, 37(7–8), 1072–1084.
Gómez-Maldonado, D., Lobato-Calleros, C., Aguirre-Mandujano, E., Leyva-Mir, S.G., Robles-Yerena, L., Vernon-Carter, E.J. (2020). Antifungal activity of mango kernel polyphenols on mango fruit infected by anthracnose. LWT – Food Science and Technology, 126, art. no. 109337.
Gupta, A.K., Gurjar, P.S., Beer, K., Pongener, A., Ravi, S.C., Singh, S., Verma, A., Singh, A., Thakur, M., Tripathy, S., Verma, D.K. (2022). A review on valorization of different byproducts of mango (Mangifera indica L.) for functional food and human health. Food Bioscience, 48, art. no. 101783.
Hernández-Maldonado, L.M., Blancas-Benítez, F.J., Zamora-Gasga, V.M., Cárdenas-Castro, A.P., Tovar, J., Sáyago-Ayerdi, S.G. (2019). In vitro gastrointestinal digestion and colonic fermentation of high dietary fiber and antioxidant-rich mango (Mangifera indica L.) “Ataulfo”-based fruit bars. Nutrients, 11(7), art. no. 1564.
Hoyos-Arbeláez, J., Blandón-Naranjo, L., Vázquez, M., Contreras-Calderón, J. (2018). Antioxidant capacity of mango fruit (Mangifera indica). An electrochemical study as an approach to the spectrophotometric methods. Food Chemistry, 266, 435–440.
Hu, K., Dars, A.G., Liu, Q., Xie, B., Sun, Z. (2018). Phytochemical profiling of the ripening of Chinese mango (Mangifera indica L.) cultivars by real-time monitoring using UPLC-ESI-QTOF-MS and its potential benefits as prebiotic ingredients. Food Chemistry, 256, 171–180.
Huang, C.-Y., Kuo, C.-H., Wu, C.-H., Kuan, A.-W., Guo, H.-R., Lin, Y.-H., Wang, P.-K. (2018). Free radical-scavenging, anti-inflammatory, and antibacterial activities of water and ethanol extracts prepared from compressional-puffing pretreated mango (Mangifera indica L.) peels. Journal of Food Quality, 2018, art. no. 1025387.
Iuit-González, M., Betancur-Ancona, D., Santos-Flores, J., Cantón-Castillo, C.G. (2019). Marmalade enriched with dietary fiber from Mango (Mangifera indica L.) peel. Revista Tecnología en Marcha, 32(1), 193–201 (in Spanish, English abstract).
Jamar, G., Estadella, D., Pisani, L.P. (2017). Contribution of anthocyanin‐rich foods in obesity control through gut microbiota interactions. BioFactors, 43(4), 507–516.
Jyotshna, Srivastava, P., Killadi, B., Shanker, K. (2015). Uni-dimensional double development HPTLC-densitometry method for simultaneous analysis of mangiferin and lupeol content in mango (Mangifera indica) pulp and peel during storage. Food Chemistry, 176, 91–98.
Kim, H., Banerjee, N., Barnes, R.C., Pfent, C.M., Talcott, S.T., Dashwood, R.H., Mertens‐Talcott, S.U. (2017). Mango polyphenolics reduce inflammation in intestinal colitis—involvement of the miR‐126/PI3K/AKT/mTOR axis in vitro and in vivo. Molecular Carcinogenesis, 56(1), 197–207.
Kim, H., Krenek, K.A., Fang, C., Minamoto, Y., Markel, M.E., Suchodolski, J.S., Talcott, S.T., Mertens-Talcott, S.U. (2018). Polyphenolic derivatives from mango (Mangifera Indica L.) modulate fecal microbiome, short-chain fatty acids production and the HDAC1/AMPK/LC3 axis in rats with DSS-induced colitis. Journal of Functional Foods, 48, 243–251.
Kim, H., Venancio, V.P., Fang, C., Dupont, A.W., Talcott, S.T., Mertens-Talcott, S.U. (2020). Mango (Mangifera indica L.) polyphenols reduce IL-8, GRO, and GM-SCF plasma levels and increase Lactobacillus species in a pilot study in patients with inflammatory bowel disease. Nutrition Research, 75, 85–94.
Kuganesan, A., Thiripuranathar, G., Navaratne, A.N., Paranagama, P.A. (2017). Antioxidant and anti-inflammatory activities of peels, pulps and seed kernels of three common mango (Mangifera indical L.) varieties in Sri Lanka. International Journal of Pharmaceutical Sciences and Research, 8(1), 70–78.
Kumaraswamy, A., Gurunagarajan, S., Pemiah, B. (2020). Scientific evaluation of anti-obesity potential of aqueous seed kernel extract of Mangifera indica Linn. in high fat diet induced obese rats. Obesity Medicine, 19, art. no. 100264.
Lagier, J.-C., Dubourg, G., Million, M., Cadoret, F., Bilen, M., Fenollar, F., Levasseur, A., Rolain, J.-M., Fournier, P.-E., Raoult, D. (2018). Culturing the human microbiota and culturomics. Nature Reviews Microbiology, 16(9), 540–550.
Lauricella, M., Lo Galbo, V., Cernigliaro, C., Maggio, A., Palumbo Piccionello, A., Calvaruso, G., Carlisi, D., Emanuele, S., Giuliano, M., D’Anneo, A. (2019). The anti-cancer effect of Mangifera indica L. peel extract is associated to γH2AX-mediated apoptosis in colon cancer cells. Antioxidants, 8(10), art. no. 422.
Lebaka, V.R., Wee, Y.-J., Ye, W., Korivi, M. (2021). Nutritional composition and bioactive compounds in three different parts of mango fruit. International Journal of Environmental Research and Public Health, 18(2), art. no. 741.
Lim, K.J.A., Cabajar, A.A., Lobarbio, C.F.Y., Taboada, E.B., Lacks, D.J. (2019). Extraction of bioactive compounds from mango (Mangifera indica L. var. Carabao) seed kernel with ethanol–water binary solvent systems. Journal of Food Science and Technology, 56(5), 2536–2544.
Lin, H., Teng, H., Wu, W., Li, Y., Lv, G., Huang, X., Yan, W. Lin, Z. (2020). Pharmacokinetic and metabolomic analyses of mangiferin calcium salt in rat models of type 2 diabetes and non-alcoholic fatty liver disease. BMC Pharmacology and Toxicology, 21(1), 1–12.
López-Cobo, A., Verardo, V., Diaz-de-Cerio, E., Segura-Carretero, A., Fernández-Gutiérrez, A., Gómez-Caravaca, A.M. (2017). Use of HPLC- and GC-QTOF to determine hydrophilic and lipophilic phenols in mango fruit (Mangifera indica L.) and its by-products. Food Research International, 100(3), 423–434.
Lopez-Martinez, L.X., Campos-Gonzalez, N., Zamora-Gasga, V.M., Domínguez-Avila, J.A., Pareek, S., Villegas-Ochoa, M.A., Sáyago-Ayerdi, S.G., González-Aguilar, G.A. (2022). Optimization of ultrasound treatment of beverage from mango and carrot with added turmeric using response surface methodology. Polish Journal of Food and Nutrition Sciences, 72(3), 287–296.
Marcillo-Parra, V., Anaguano, M., Molina, M., Tupuna-Yerovi, D.S., Ruales, J. (2021). Characterization and quantification of bioactive compounds and antioxidant activity in three different varieties of mango (Mangifera indica L.) peel from the Ecuadorian region using HPLC-UV/VIS and UPLC-PDA. NFS Journal, 23, 1–7.
Martínez-Ramos, T., Benedito-Fort, J., Watson, N.J., Ruiz-López, I.I., Che-Galicia, G., Corona-Jiménez, E. (2020). Effect of solvent composition and its interaction with ultrasonic energy on the ultrasound-assisted extraction of phenolic compounds from Mango peels (Mangifera indica L.). Food and Bioproducts Processing, 122, 41–54.
Melo, P.E.F., Silva, A.P.M., Marques, F.P., Ribeiro, P.R.V., Souza Filho, M.S.M., Brito, E.S., Lima, J.R., Azeredo, H.M.C. (2019). Antioxidant films from mango kernel components. Food Hydrocolloids, 95, 487–495.
Mutua, J.K., Imathiu, S., Owino, W. (2017). Evaluation of the proximate composition, antioxidant potential, and antimicrobial activity of mango seed kernel extracts. Food Science and Nutrition, 5(2), 349–357.
Mwaurah, P.W., Kumar, S., Kumar, N., Panghal, A., Attkan, A.K., Singh, V.K., Garg, M.K. (2020). Physicochemical characteristics, bioactive compounds and industrial applications of mango kernel and its products: A review. Comprehensive Reviews in Food Science and Food Safety, 19(5), 2421–2446.
Navarro, M., Arnaez, E., Moreira, I., Quesada, S., Azofeifa, G., Wilhelm, K., Vargas, F., Chen, P. (2019). Polyphenolic characterization, antioxidant, and cytotoxic activities of Mangifera indica cultivars from Costa Rica. Foods, 8(9), art. no. 384.
Nawab, A., Alam, F., Haq, M.A., Haider, M.S., Lutfi, Z., Kamaluddin, S., Hasnain, A. (2018). Innovative edible packaging from mango kernel starch for the shelf life extension of red chili powder. International Journal of Biological Macromolecules, 114, 626–631.
Nawab, A., Alam, F., Hasnain, A. (2017). Mango kernel starch as a novel edible coating for enhancing shelf-life of tomato (Solanum lycopersicum) fruit. International Journal of Biological Macromolecules, 103, 581–586.
Nguyen, T.V.L., Nguyen, Q.D., Nguyen, P.B.D. (2022). Drying kinetics and changes of total phenolic content, antioxidant activity and color parameters of mango and avocado pulp in refractance window drying. Polish Journal of Food and Nutrition Sciences, 72(1), 27–38.
Norma Oficial Mexicana (1997). Especificaciones sanitarias para alimentos envasados en recipientes de cierre hermético y sometidos a tratamiento térmico (NOM-130-SSA1-1995) (in Spanish).
Oliver-Simancas, R., Labrador-Fernández, L., Díaz-Maroto, M.C., Pérez-Coello, M.S., Alañón, M.E. (2021). Comprehensive research on mango by-products applications in food industry. Trends in Food Science and Technology, 118, 179–188.
Pacheco-Ordaz, R., Antunes-Ricardo, M., Gutiérrez-Uribe, J.A., González-Aguilar, G.A. (2018a). Intestinal permeability and cellular antioxidant activity of phenolic compounds from mango (Mangifera indica cv. Ataulfo) peels. International Journal of Molecular Sciences, 19(2), art. no. 514.
Pacheco‐Ordaz, R., Wall‐Medrano, A., Goñi, M.G., Ramos‐Clamont‐Montfort, G., Ayala‐Zavala, J.F., González‐Aguilar, G.A. (2018b). Effect of phenolic compounds on the growth of selected probiotic and pathogenic bacteria. Letters in Applied Microbiology, 66(1), 25–31.
Patiño-Rodríguez, O., Bello-Pérez, L.A., Agama-Acevedo, E., Pacheco-Vargas, G. (2021). Effect of deep frying unripe mango kernel flour extrudate: Physicochemical, microstructural and starch digestibility characteristics. LWT – Food Science and Technology, 145, art. no. 111267.
Peanparkdee, M., Iwamoto, S. (2022). Encapsulation for improving in vitro gastrointestinal digestion of plant polyphenols and their applications in food products. Food Reviews International, 38(4), 335–353.
Pérez-Chabela, M.L., Cebollón-Juárez, A., Bosquez-Molina, E., Totosaus, A. (2022). Mango peel flour and potato peel flour as bioactive ingredients in the formulation of functional yogurt. Food Science and Technology, 42, art. no. e38220.
Rodríguez-González, S., Gutiérrez-Ruíz, I.M., Pérez-Ramírez, I.F., Mora, O., Ramos-Gomez, M., Reynoso-Camacho, R. (2017). Mechanisms related to the anti-diabetic properties of mango (Mangifera indica L.) juice by-product. Journal of Functional Foods, 37, 190–199.
Safdar, M.N., Kausar, T., Nadeem, M. (2017). Comparison of ultrasound and maceration techniques for the extraction of polyphenols from the mango peel. Journal of Food Processing and Preservation, 41(4), art. no. e13028.
Sánchez-Camargo, A.P., Ballesteros-Vivas, D., Buelvas-Puello, L.M., Martinez-Correa, H.A., Parada-Alfonso, F., Cifuentes, A., Ferreira, S.R.S., Gutiérrez, L.F. (2021). Microwave-assisted extraction of phenolic compounds with antioxidant and anti-proliferative activities from supercritical CO2 pre-extracted mango peel as valorization strategy. LWT – Food Science and Technology, 137, art. no. 110414.
Sánchez-Camargo, A.P., Gutiérrez, L.F., Vargas, S.M., Martinez-Correa, H.A., Parada-Alfonso, F., Narváez-Cuenca, C.E. (2019). Valorisation of mango peel: Proximate composition, supercritical fluid extraction of carotenoids, and application as an antioxidant additive for an edible oil. The Journal of Supercritical Fluids, 152, art. no. 104574.
Santana, Á.L., Queirós, L.D., Martinez, J., Macedo, G.A. (2019). Pressurized liquid- and supercritical fluid extraction of crude and waste seeds of guarana (Paullinia cupana): Obtaining of bioactive compounds and mathematical modeling. Food and Bioproducts Processing, 117, 194–202.
Sáyago-Ayerdi, S.G., Zamora-Gasga, V.M., Venema, K. (2019). Prebiotic effect of predigested mango peel on gut microbiota assessed in a dynamic in vitro model of the human colon (TIM-2). Food Research International, 118, 89–95.
Soria-Lara, D.M., Jiménez-García, S.N., Botello-Álvarez, J.E., Miranda-López, R. (2020). Main changes on the polyphenols profile and antioxidant capacity in Manila mango (Mangifera indica L.). Archivos Latinoamericanos de Nutrición, 70(4), 269–281.
Tan, L., Jin, Z., Ge, Y., Nadeem, H., Cheng, Z., Azeem, F., Zhan, R. (2020). Comprehensive ESI-Q TRAP-MS/MS based characterization of metabolome of two mango (Mangifera indica L) cultivars from China. Scientific Reports, 10(1), art. no. 20017.
Tian, L., Tan, Y., Chen, G., Wang, G., Sun, J., Ou, S., Chen, W., Bai, W. (2019). Metabolism of anthocyanins and consequent effects on the gut microbiota. Critical Reviews in Food Science and Nutrition, 59(6), 982–991.
Tirado-Kulieva, V., Atoche-Dioses, S., Hernández-Martínez, E. (2021). Phenolic compounds of mango (Mangifera indica) by-products: Antioxidant and antimicrobial potential, use in disease prevention and food industry, methods of extraction and microencapsulation. Scientia Agropecuaria, 12(2), 283–293.
Torres-León, C., de Azevedo Ramos, B., dos Santos Correia, M.T., Carneiro-da-Cunha, M.G., Ramirez-Guzman, N., Alves, L.C., Brayner, F.A., Ascacio-Valdes, J., Álvarez-Pérez, O.B., Aguilar, C.N. (2021). Antioxidant and anti-staphylococcal activity of polyphenolic-rich extracts from Ataulfo mango seed. LWT – Food Science and Technology, 148, art. no. 111653.
Torres-León, C., Rojas, R., Contreras-Esquivel, J.C., Serna-Cock, L., Belmares-Cerda, R.E., Aguilar, C.N. (2016). Mango seed: Functional and nutritional properties. Trends in Food Science and Technology, 55, 109–117.
Torres-León, C., Rojas, R., Serna-Cock, L., Belmares-Cerda, R., Aguilar, C.N. (2017). Extraction of antioxidants from mango seed kernel: Optimization assisted by microwave. Food and Bioproducts Processing, 105, 188–196.
Torres-León, C., Vicente, A.A., Flores-López, M.L., Rojas, R., Serna-Cock, L., Alvarez-Pérez, O.B., Aguilar, C.N. (2018). Edible films and coatings based on mango (var. Ataulfo) by-products to improve gas transfer rate of peach. LWT – Food Science and Technology, 97, 624–631.
Vazquez‐Olivo, G., Antunes‐Ricardo, M., Gutiérrez‐Uribe, J.A., Osuna‐Enciso, T., León‐Félix, J., Heredia, J.B. (2019). Cellular antioxidant activity and in vitro intestinal permeability of phenolic compounds from four varieties of mango bark (Mangifera indica L.). Journal of the Science of Food and Agriculture, 99(7), 3481–3489.
Velderrain-Rodríguez, G.R., Torres-Moreno, H., Villegas-Ochoa, M.A., Ayala-Zavala, J.F., Robles-Zepeda, R.E., Wall-Medrano, A., González-Aguilar, G.A. (2018). Gallic acid content and an antioxidant mechanism are responsible for the antiproliferative activity of ‘Ataulfo’ mango peel on LS180 cells. Molecules, 23(3), art. no. 695.
Vimalraj, S., Ashokkumar, T., Saravanan, S. (2018). Biogenic gold nanoparticles synthesis mediated by Mangifera indica seed aqueous extracts exhibits antibacterial, anticancer and anti-angiogenic properties. Biomedicine and Pharmacotherapy, 105, 440–448.
Wu, P., Bhattarai, R.R., Dhital, S., Deng, R., Chen, X.D., Gidley, M.J. (2017). In vitro digestion of pectin- and mango-enriched diets using a dynamic rat stomach-duodenum model. Journal of Food Engineering, 202, 65–78.
Ye, S., Shah, B.R., Li, J., Liang, H., Zhan, F., Geng, F., Li, B. (2022). A critical review on interplay between dietary fibers and gut microbiota. Trends in Food Science and Technology, 124, 237–249.