Current issue
In press
Archive
About the Journal
Scope
Editorial Board
Indexed
Subscription
Contact
Editorial Policies
Peer Review Policy
For Reviewers
Research Ethics Policy
Plagiarism
Informed Consent Policy
Conflict of Interest Policy
Open Access Policy
Corrections, Retractions and Expressions of Concern
Advertising Policy
Instructions for Authors
News
New IMPACT FACTOR
Volume 70 Authors' Index
Volume 70 Reviewers' Index
Dietary recommendations during the COVID-19 pandemic. Statement of the Committee of Human Nutrition Science of the Polish Academy of Sciences
Our new CiteScore2020 from SCOPUS
June 2021 Issue has just been published
September 2021 issue has just been released
Volume 71's Reviewers Index
Our new Impact Factor and Cite Score
Editorial Policies
Peer Review Policy
For Reviewers
Research Ethics Policy
Plagiarism
Informed Consent Policy
Conflict of Interest Policy
Open Access Policy
Corrections, Retractions and Expressions of Concern
Advertising Policy
News
New IMPACT FACTOR
Volume 70 Authors' Index
Volume 70 Reviewers' Index
Dietary recommendations during the COVID-19 pandemic. Statement of the Committee of Human Nutrition Science of the Polish Academy of Sciences
Our new CiteScore2020 from SCOPUS
June 2021 Issue has just been published
September 2021 issue has just been released
Volume 71's Reviewers Index
Our new Impact Factor and Cite Score
ORIGINAL ARTICLE
Black Trumpet, Craterellus cornucopioides (L.) Pers.: Culinary Mushroom with Angiotensin Converting Enzyme Inhibitory and Cytotoxic Activity
| 1 | Department of Pharmacognosy, University of Belgrade, Faculty of Pharmacy, Vojvode Stepe 450, 11322 Belgrade, Serbia |
| 2 | Department of Organic Chemistry, Faculty of Technology, University of Niš, Bulevar Oslobođenja 124, 16000 Leskovac, Serbia |
| 3 | Institute of Public Health of Serbia “Dr Milan Jovanovic Batut”, dr Subotića 5, 11000 Belgrade, Serbia |
| 4 | Experimental Oncology, Institute for Oncology and Radiology of Serbia, Pasterova 11, 11000 Belgrade, Serbia |
| 5 | Institute of Public Health Kragujevac, Nikole Pašića 1, 34000 Kragujevac, Serbia |
CORRESPONDING AUTHOR
Tatjana Kundakovic-Vasović
Department of Pharmacognosy, Faculty of Pharmacy, University of Belgrade, Belgrade, Belgrade, Serbia
Department of Pharmacognosy, Faculty of Pharmacy, University of Belgrade, Belgrade, Belgrade, Serbia
Submission date: 2021-11-01
Final revision date: 2022-05-03
Acceptance date: 2022-05-09
Online publication date: 2022-06-06
Publication date: 2022-06-06
Pol. J. Food Nutr. Sci. 2022;72(2):171–181
KEYWORDS
TOPICS
Gas chromatographyLiquid chromatographyMushroomsDietary fiberFlavours/AromasPhenolic compoundsVitamins
ABSTRACT
Nutritional value and chemical composition, including the content of vitamins, fatty acids, 5’-nucleotides and nucleosides and amino acids, as well as biological activities, including antioxidant, angiotensin converting enzyme (ACE) inhibitory and cytotoxic activity of black trumpet (Craterellus cornucopioides (L.) Pers.) were tested in vitro. C. cornucopioides was low in energy, fat and carbohydrate contents, but rich in dietary fibre, especially β-glucan as well as niacin and α-tocopherol. The content of essential and non-essential free amino acids was 1.49 and 5.48 mg/g dry weight (dw). The nucleosides and 5’-nucleotides were determined at 1.84 and 3.99 mg/g dw, respectively. The share of unsaturated fatty acids (UFAs) was 75.92% with oleic acid as the major UFA. Cyclohexane and dichloromethane extracts expressed significant cytotoxic activity against selected cell lines, human epithelial cervical cancer cells (HeLa), adenocarcinomic human alveolar basal epithelial cells (A549), colorectal cancer cells (LS174) and normal MRC-5 human embryonic lung fibroblast cells (IC50 of 78.3–155.6 μg/mL). ACE inhibitory activity of the aqueous extract was strong with an IC50 of 0.74 μg/mL. It can be concluded that black trumpet is a good source of nutrients, such as vitamins, dietary fibres, amino acids, nucleotides and fatty acids, which contribute to the overall nutritional value of this fungus with potential for ACE inhibitory activity and use in anti-hypertensive diet.
FUNDING
This research was funded by the Ministry of Education, Science and Technological Development, Republic of Serbia through Grant Agreement with University of Belgrade-Faculty of Pharmacy No: 451-03-9/2021-14/200161.
CONFLICT OF INTEREST
The authors confirm that this article content has no conflict of interest.
REFERENCES (52)
1.
Abugri, D., McElhenney, W., William, K. (2016). Fatty acid profiling in selected cultivated edible and wild medicinal mushrooms in Southern United States. Journal of Experimental Food Chemistry, 2(1), art. no. 100108. https://doi.org/10.4172/2472-0....
2.
AOAC. (1995). Official Methods of Analysis (16th ed.). Arlighton, VA: Association of Official Analytical Chemists.
3.
Barros, L., Cruz, T., Baptista, P., Estevinho, L., Ferreira, I. (2008). Wild and commercial mushrooms as source of nutrients and nutraceuticals. Food and Chemical Toxicology, 46(8), 2742–2747. https://doi.org/10.1016/j.fct.....
4.
Beluhan, S., Ranogajec, A. (2011). Chemical composition and non-volatile components of Croatian wild edible mushrooms. Food Chemistry, 124(3), 1076–1082. https://doi.org/10.1016/j.food....
5.
Cağlarirmak, N. (2011). Chemical composition and nutrition value of dried cultivated culinary–medicinal mushrooms from Turkey. International Journal of Medicinal Mushrooms, 13, 351–356. https://doi.org/10.1615/IntJMe....
6.
Cardwell, G., Bornman, J.F., James, A.P., Black, L.J. (2018). A review of mushrooms as a potential source of dietary vitamin D. Nutrients, 10(10), art. no. 1498. https://doi.org/10.3390/nu1010....
7.
Chen, P., Qin, H.J., Li, Y.W., Ma, G.X., Yang, J.S., Wang, Q. (2020). Study on chemical constituents of an edible mushroom Volvariella volvacea and their antitumor activity in vitro. Natural Product Research, 34(10), 1417–1422. https://doi.org/10.1080/147864....
8.
Cheung, P.C.K. (2010). The nutritional and health benefits of mushrooms. Nutrition Bulletin, 35(4), 292-299. https://doi.org/10.1111/j.1467....
9.
Cho, I.H., Choi, H.K., Kim, Y. (2010). Comparison of umami-taste active components in the pileus and stipe of pine-mushrooms (Tricholoma matsutake Sing.) of different grades. Food Chemistry, 118(3), 804–807. https://doi.org/10.1016/j.food....
10.
Choi, H.S., Cho, H.Y., Yang, H.C., Ra, K.S., Suh, H.J. (2001). Angiotensin I-converting enzyme inhibitor from Grifola frondosa. Food Research International, 34(2–3), 177–182. https://doi.org/10.1016/S0963-....
11.
Colak, A., Faiz, Ö., Sesli, E. (2009). Nutritional composition of some wild edible mushrooms. Turkish Journal of Biochemistry, 34(1), 25–31.
12.
Gil-Ramirez, A., Clavijo, C., Palanisamy, M., Soler-Rivas, C., Ruiz-Rodrigez, A., Martin, F., Reglero, G., Perez, M. (2011). Edible mushrooms as potential sources of new hypocholesterolemic compounds. (2011). Proceedings of the 7th International Conference on Mushroom Biology and Mushroom Products (ICMBMP7), 4-7 October 2011, Arcachon, France, 110–119.
13.
Grundy, S.M. (2013). Cholesterol: Factors determining blood levels. In B. Caballero (ed.), Encyclopedia of Human Nutrition (3rd edition). London, United Kingdom: Academic Press, pp. 335–340. https://doi.org/10.1016/B978-0....
14.
Guo, H., Diao, Q., Hou, D., Li, Z., Zhou, Z., Feng, T., Liu, J. (2017a). Sesquiterpenoids from cultures of the edible mushroom Craterellus cornucopioides. Phytochemistry Letters, 21, 114–117. https://doi.org/10.1016/j.phyt....
15.
Guo, H., Diao, Q.P., Zhang, B., Feng, T. (2017b). Two new illudane sesquiterpenoids and one new menthane monoterpene from cultures of Craterellus cornucopioides. Journal of Asian Natural Products Research, 21(2), 123–128. https://doi.org/10.1080/102860....
16.
Heleno, S.A., Barros, L., Sousa, M.J., Martins, A., Santos-Buelga, C., Ferrerira, I.C.F.R. (2011). Targeted metabolites analysis in wild Boletus species. LWT – Food Science and Technology, 44(6), 1343–1348. https://doi.org/10.1016/j.lwt.....
18.
Jang, J.H., Jeong, S.C., Kim, J.H., Lee, Y.H., Ju, Y.C., Lee, J.S. (2011). Characterisation of a new antihypertensive angiotensin I-converting enzyme inhibitory peptide from Pleurotus cornucopiae. Food Chemistry, 127(2), 412–418. https://doi.org/10.1016/j.food....
19.
Jung, E.B., Jo, J.H., Cho, S.M. (2009). Hypoglycemic and angiotension converting enzyme inhibitory effect of water and ethanol extracts from Haesongi mushroom (Hypsizigus marmoreus). Food Science and Biotechology, 18(2), 541–545. https://www.earticle.net/Artic....
20.
Khatun, K., Mahtab, H., Khanam, P.A., Sayeed, M.A., Khan, K.A. (2007). Oyster mushroom reduced blood glucose and cholesterol in diabetic subjects. Mymensingh Medical Journal, 16(1), 94–99. https://doi.org/10.3329/mmj.v1....
21.
Kolundžić, M., Stanojković, T., Radović, J., Tačić, A., Dodevska, M., Milenković, M., Sisto, F., Masia, C., Farronato, G., Nikolić, V., Kundaković, T. (2017). Cytotoxic and antimicrobial activities of Cantharellus cibarius Fr. (Cantarellaceae). Journal of Medicinal Food, 20(8), 790–796. https://doi.org/10.1089/jmf.20....
22.
Kosanić, M., Ranković, B., Stanojković, T., Radović-Jakovljević, M., Ćirić, A., Grujičić, D., Milošević-Djordjević, O. (2019). Craterellus cornucopioides edible mushroom as source of biologically active compounds. Natural Product Communications, 14(5), 1–6. https://doi.org/10.1177/193457....
23.
Kundaković, T., Kolundžić, M. (2013). Therapeutic properties of mushrooms in managing adverse effects in the metabolic syndrome. Current Topics in Medicinal Chemistry, 13(21), 2734–2744. https://doi.org/10.2174/156802....
24.
Lee, D.H., Kim, J.H., Park, J.S., Choi, Y.J., Lee, J.S. (2004). Isolation and characterization of a novel angiotensin I-converting enzyme inhibitory peptide derived from the edible mushroom Tricholoma giganteum. Peptides, 25(4), 621–627. https://doi.org/10.1016/j.pept....
25.
Liu, Y.T., Sun, J., Luo, Z.Y., Rao, S.Q., Su, Y.J., Xu, R.R., Yang, Y.J. (2012). Chemical composition of five wild edible mushrooms collected from Southwest China and their antihyperglycemic and antioxidant activity. Food and Chemical Toxicology, 50(5), 1238–1244. https://doi.org/10.1016/j.fct.....
26.
Lo, H.C., Hsu, T.H., Lin, F.Y., Wasser, S.P., Chen, Y.H., Lee, C.H. (2012). Effects of yellow brain culinary-medicinal mushroom, Tremella mesenterica Ritz.:Fr. (Higher basidiomycetes), on immune function in normal and type 1 diabetic rats. International Journal of Medicinal Mushrooms, 14(5), 447–457. https://doi.org/10.1615/IntJMe....
27.
Mau, J.L. (2005). The umami taste of edible and medicinal mushrooms. International Journal of Medicinal Mushrooms, 7(1-2), 119–126. https://doi.org/10.1615/IntJMe....
28.
Mirończuk-Chodakowska, I., Witkowska, A.M., Zujko, M.E., Terlikowska, K.M. (2017). Quantitative evaluation of 1,3,1,6 β-D-glucan contents in wild-growing species of edible Polish mushrooms. Roczniki Państwowego Zakładu Higieny, 68(3), 281–290.
29.
O’Callaghan, Y.C., O’Brien, N.M., Kenny, O., Harrington, T., Brunton, N., Smyth, T.J. (2015). Anti-inflammatory effects of wild Irish mushroom extracts in RAW264.7 mouse macrophage cells. Journal of Medicinal Food, 18(2), 202–207. https://doi.org/10.1089/jmf.20....
30.
Palacios, I., Lozano, M., Moro, C., D’Arrigo, M., Rostagno, M.A., Martínez, J.A., García-Lafuente, A., Guillamón, E., Villares, A. (2011). Antioxidant properties of phenolic compounds occurring in edible mushrooms. Food Chemistry, 128(3), 674–678. https://doi.org/10.1016/j.food....
31.
Pandya, U., Dhuldhaj, U., Sahay, N.S. (2019). Bioactive mushroom polysaccharides as antitumor: an overview. Natural Product Research, 33(18), 2668–2680. https://doi.org/10.1080/147864....
32.
Phan, C., Wang, J., Cheah, S., Naidu, M., David, P., Sabarantam, V. (2018). A review on the nucleic acid constituents in mushrooms: nucleobases, nucleosides and nucleotide. Critical Reviews in Biotechnology, 38(5), 762–777. https://doi.org/10.1080/073885....
33.
Phat, C., Moon, B., Lee, C. (2016). Evaluation of umami taste in mushroom extracts by chemical analysis, sensory evaluation, and an electronictongue system. Food Chemisty, 192, 1068–1077. https://doi.org/10.1016/j.food....
34.
Ranogajec, A., Beluhan, S., Šmit, Z. (2009). Analysis of nucleosides and monophosphate nucleotides from mushrooms with reversed-phase HPLC. Journal of Separation Science, 33(8), 1024–1033. https://doi.org/10.1002/jssc.2....
35.
Ribeiro, B., Andrade, P., Silva, B., Baptista, P., Seabra, R., Valentão, P. (2008). Comparative study on free amino acid composition of wild edible mushroom species. Journal of Agricultural and Food Chemistry, 56(22), 10973–10979. https://doi.org/10.1021/jf8020....
36.
Sagar, P.S., Das, U.N., Koratkar, R., Ramesh, G., Padma, M., Kumar, G.S. (1992). Cytotoxic action of cis-unsaturated fatty acids on human cervical carcinoma (HeLa) cells: relationship to free radicals and lipid peroxidation and its modulation by calmodulin antagonists. Cancer Letters, 63(3), 189–198. https://doi.org/10.1016/0304-3....
37.
Sakamoto, Y., Takeuchi, A., Sato, T., Obara, K., Takai, K., Fujino, K., Hirose, T., Inagaki, Y. (2001). Identification of antihypertensive substance in an aqueous extract from fruit body of Mycoleptodonoides aitchisonii. Oyo Yakuri/Pharmacometrics, 61, 221–229.
38.
Silva Figueiredo, P., Carla Inada, A., Marcelino, G., Maiara Lopes Cardozo, C., de Cássia Freitas, K., de Cássia Avellaneda Guimarães, R., Pereira de Castro, A., Aragão do Nascimento, V., Aiko Hiane, P. (2017). Fatty acids consumption: the role metabolic aspects involved in obesity and its associated disorders. Nutrients, 9(10), art. no. 1158. https://doi.org/10.3390/nu9101....
39.
Teichmann, A., Dutta, P.C., Staffas, A., Jägerstad, M. (2007). Sterol and vitamin D2 concentrations in cultivated and wild grown mushrooms: Effects of UV irradiation. LWT – Food Science and Technology, 40(5), 815–822. https://doi.org/10.1016/j.lwt.....
40.
Tucker, J.M., Townsend, D.M. (2005). Alpha-tocopherol: roles in prevention and therapy of human disease. Biomedicine & Pharmacotherapy, 59(7), 380–387. https://doi.org/10.1016/j.biop....
41.
Ušjak, L., Sofrenić, I., Tešević, V., Drobac, M., Niketić, M., Petrović, S. (2019). Fatty acids, sterols, and triterpenes of the fruits of 8 Heracleum taxa. Natural Product Communications, 14(6). https://doi.org/10.1177/193457....
42.
Vamanu, E., Nita, S. (2014). Biological activity of fluidized bed ethanol extracts from several edible mushrooms. Food Science and Biotechnology, 23(5) 1483–1490. https://doi.org/10.1007/s10068....
43.
Vasdekis, E.P., Karkabounas, A., Giannakopoulos, I., Savvas, D., Lekka, M. (2018). Screening of mushrooms bioactivity: piceatannol was identified as a bioactive ingredient in the order Cantharellales. European Food Research and Technology, 244, 861–871. https://doi.org/10.1007/s00217....
44.
Venditti, A., Frezza, C., Sciubba, F., Serafini, M., Bianco, A. (2017). Primary and secondary metabolites of an European edible mushroom and its nutraceutical value: Suillusbellinii (Inzenga) Kuntze. Natural Product Research, 31(16), 1910–1919. https://doi.org/10.1080/147864....
45.
Wang, X.M., Zhang, J., Wu, L.H., Zhao, Y.L., Li, T., Li, J.Q., Wang, Y.Z., Liu, H.G. (2014). A mini-review of chemical composition and nutritional value of edible wild-grown mushroom from China. Food Chemistry, 151, 279–285. https://doi.org/10.1016/j.food....
46.
Watanabe, F., Schwarz, J., Takenaka, S., Miyamoto, E., Ohishi, N., Nelle, E., Hochstrasser, R., Yabuta, Y. (2012). Characterization of vitamin B12 compounds in the wild edible mushrooms black trumpet (Craterellus cornucopioides) and golden chanterelle (Cantharellus cibarius). Journal of Nutritional Science and Vitaminology, 58(6), 438–441. https://doi.org/10.3177/jnsv.5....
47.
Wheeler, S., Jordan, P. (2007). A Practical Encyclopedia of Mushrooms (Praktična enciklopedija pečuraka). JRJ: Zemun-Belgrade, Serbia, p. 54.
48.
Williams, B., Mancia, G., Spiering, W., Rosei, E.A., Azizi, M., Burnier, M., Clement, D.L., Coca, A., De Simone, G., Dominiczak, A., Kahan, T., Mahfoud, F., Redon, J., Ruilope, L., Zanchetti, A., Kerins, M., Kjeldsen, S.E., Kreutz, R., Laurent, S., Lip, G.Y.H., McManus, R., Narkiewicz, K., Ruschitzka, F., Schmieder, R.E., Shlyakhto, E., Tsioufis, C., Aboyans, V., Desormais, I. (2018). ESC Scientific Document Group. 2018 ESC/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH). European Heart Journal, 39(33), 3021–3104. https://doi.org/10.1093/eurhea....
49.
World Health Organization Cardiovascular diseases factsheet, 11 June 2021. https://www.who.int/news-room/...) [last visited 20.5.2022].
50.
Wu, Q., Li, Y., Peng, K., Wang, X. L., Ding, Z., Liu, L., Xu, P., Liu, G.Q. (2019). Isolation and characterization of three antihypertension peptides from the mycelia of Ganoderma lucidum (Agaricomycetes). Journal of Agricultural and Food Chemistry, 67(29), 8149–8159. https://doi.org/10.1021/acs.ja....
51.
Yamaguchi, S., Yoshikawa, T., Iikeda, S., Ninomiya, T. (1971). Measurement of the relative taste intensity of some L-amino acids and 5’-nucleotides. Journal of Food Science, 36(6) 846–849. https://doi.org/10.1111/j.1365....
52.
Zhao, H., Zhang, H., Yang, S. (2014). Phenolic compounds and its antioxidant activities in ethanolic extracts from seven cultivars of Chinese jujube. Food Science and Human Wellness, 3(3-4), 183–190. https://doi.org/10.1016/j.fshw....
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.