Search for Author, Title, Keyword
Current Approaches for Enhanced Expression of Secondary Metabolites as Bioactive Compounds in Plants for Agronomic and Human Health Purposes
 
More details
Hide details
Publication date: 2013-06-30
 
Pol. J. Food Nutr. Sci. 2013;63(2):67–78
 
KEYWORDS
ABSTRACT
The study of secondary metabolism in plants is an important source for the discovery of bioactive compounds with a wide range of applications. Today these bioactive compounds derived from plants are important drugs such as antibiotics, and agrochemicals substitutes, also this have been economically important as flavors and fragrances, dyes and pigments, and food preservatives. Many of the drugs sold today are synthetic modifications of naturally obtained substances. There is no rigid scheme for classifying secondary metabolites can be divided into different groups based on their chemical components, function and biosynthesis: terpenoids and steroids, fatty acid-derived substances and polyketides, alkaloids, phenolic compounds, non-ribosomal polypeptides and enzyme cofactors. The increasing commercial importance of these chemical compounds has resulted in a great interest in secondary metabolism, particularly the possibility of altering the production of bioactive plant metabolites by means of tissue culture technology and metabolomics. In today’s world the use of bioactive compounds derived from plants plays important roles in pharmaceutical applications. This review presents information about these metabolites and their applications as well as their importance in agronomy and bioactive effects on human health as nutraceuticals. Also this review includes the new tendencies to produce these bioactive compounds under different stresses conditions such as biotic and abiotic stress that could be included in production systems.
 
CITATIONS (52):
1.
Biosystems Engineering: Biofactories for Food Production in the Century XXI
Lina Garcia-Mier, Sandra Jimenez-Garcia, Angela Chapa-Oliver, Laura Mejia-Teniente, Rosalía Ocampo-Velazquez, Enrique Rico-García, Ana Feregrino-Pérez, Ramon Guevara-Gonzalez, Irineo Torres-Pacheco
 
2.
Ectopic expression of amaranth seed storage albumin modulates photoassimilate transport and nutrient acquisition in sweetpotato
Shubhendu Shekhar, Lalit Agrawal, Divya Mishra, Alak Buragohain, Mullath Unnikrishnan, Chokkappan Mohan, Subhra Chakraborty, Niranjan Chakraborty
Scientific Reports
 
3.
Assessment of growth and phytochemical quality of Gynura procumbens through nitrogen, potassium fertilization and evapotranspiration replacement interaction
Bukhori Mohamad, Hawa Jaafar, Ali Ghasemzadeh, Uma Sinniah, Gayatri Karipaya, Keezrawati Yusuf
Asia Pacific Journal of Molecular Biology and Biotechnology
 
4.
Silybin content and overexpression of chalcone synthase genes in Silybum marianum L. plants under abiotic elicitation
Hoda El-Garhy, Salah Khattab, Mahmoud Moustafa, Ali Abou, Azeiz Abdel, Abeer Elhalwagi, Sherif El
Plant Physiology and Biochemistry
 
5.
Metabolic Engineering for Bioactive Compounds
Savita Khatri, Reena Saini, Anil Chhillar
 
6.
Sweeteners
Luciana Angelini, Andrea Martini, Barbara Passera, Silvia Tavarini
 
7.
Fungal Nanobionics: Principles and Applications
Shasmita, Nihar Singh, Sakti Rath, Shashikanta Behera, Soumendra Naik
 
8.
The Effect of Heat Processing on Chemical Composition and Antioxidative Activity of Tea Made from Barley Sprouts and Wheat Sprouts
Mohammad Islam, Deok‐Su Yu, Young‐Tack Lee
Journal of Food Science
 
9.
Pharmacotherapeutic potential of phytochemicals: Implications in cancer chemoprevention and future perspectives
Varinder Kaur, Manish Kumar, Ajay Kumar, Kamaldeep Kaur, Varinderpal Dhillon, Satwinderjeet Kaur
Biomedicine & Pharmacotherapy
 
10.
Isolation and molecular identification of two novel cyanobacterial isolates obtained from a stressed aquatic system
Omnia Badr, Ibrahim EL-Shawaf, Hoda El-Garhy, Mahmoud Moustafa
Gene Reports
 
11.
Physiological responses and fruit quality of four peach cultivars under sustained and cyclic deficit irrigation in center-west of Tunisia
Monia Guizani, Samia Dabbou, Samira Maatallah, Giuseppe Montevecchi, Hichem Hajlaoui, Mourad Rezig, Ahmed Helal, Soumaya Kilani-Jaziri
Agricultural Water Management
 
12.
A need for a transdisciplinary environment: the Plant Pathways Elucidation Project
Robert Reid, Cory Brouwer, Eric Jackson, Mary Lila
Trends in Plant Science
 
13.
Plant Diseases - Current Threats and Management Trends
Ramírez-Gómez S., Jiménez-García N., Campos Beltrán, García Lourdes
 
14.
Transcriptome Analysis of Secondary Metabolism Pathway, Transcription Factors, and Transporters in Response to Methyl Jasmonate in Lycoris aurea
Rong Wang, Sheng Xu, Ning Wang, Bing Xia, Yumei Jiang, Ren Wang
Frontiers in Plant Science
 
15.
Combined Effects of Water Deficit, Exogenous Ethylene Application and Root Symbioses on Trigonelline and ABA Accumulation in Fenugreek
Simin Irankhah, Fabiano Sillo, Luca Nerva, Ali Ganjeali, Raffaella Balestrini, Walter Chitarra
Applied Sciences
 
16.
Athelia (Sclerotium) rolfsii in Allium sativum: potential biocontrol agents and their effects on plant metabolites
VYTÓRIA CAVALCANTI, NEILTON ARAÚJO, KÁTIA SCHWANESTRADA, MOACIR PASQUAL, JOYCE DÓRIA
Anais da Academia Brasileira de Ciências
 
17.
Characterization and in vitro cytotoxicity of phytochemicals from Aspilia africana obtained using green extraction techniques
Irvine Niyonizigiye, David Nkurunziza, Daniel Ngabire, Adane Gitachew, Byung Chun, Gun-Do Kim
South African Journal of Botany
 
18.
Sweeteners
Luciana Angelini, Andrea Martini, Barbara Passera, Silvia Tavarini
 
19.
Therapeutic Foods
Sandra Jimenez-Garcia, Moises Vazquez-Cruz, Lina Garcia-Mier, Luis Contreras-Medina, Ramon Guevara-González, Juan Garcia-Trejo, Ana Feregrino-Perez
 
20.
Transformation of Lettuce with rol ABC Genes: Extracts Show Enhanced Antioxidant, Analgesic, Anti-Inflammatory, Antidepressant, and Anticoagulant Activities in Rats
Hammad Ismail, Erum Dilshad, Mohammad Waheed, Bushra Mirza
Applied Biochemistry and Biotechnology
 
21.
Expression analysis of Cell wall invertase under abiotic stress conditions influencing specialized metabolism in Catharanthus roseus
M. Nishanth, S. Sheshadri, Sudarshan Rathore, S. Srinidhi, Bindu Simon
Scientific Reports
 
22.
Feed Additives
E. Christaki, Ilias Giannenas, Eleftherios Bonos, P. Florou-Paneri
 
23.
Combination of Plant Metabolic Modules Yields Synthetic Synergies
Fatemeh Rajabi, Ernst Heene, Jan Maisch, Peter Nick, Gabriel Agbor
PLOS ONE
 
24.
Sensory quality and flavour of alginate coated and repetitive pulsed light treated fresh-cut cantaloupes (Cucumis melo L. Var. Reticulatus Cv. Glamour) during storage
Pei Koh, Mohd Noranizan, Roselina Karim, Hanani Nur
Journal of Food Science and Technology
 
25.
Linking traits of invasive plants with ecosystem services and disservices
Marija Milanović, Sonja Knapp, Petr Pyšek, Ingolf Kühn
Ecosystem Services
 
26.
Controlled water deficit as abiotic stress factor for enhancing the phytochemical content and adding-value of crops
Mario González-Chavira, María Herrera-Hernández, Horacio Guzmán-Maldonado, José Pons-Hernández
Scientia Horticulturae
 
27.
Secondary metabolism of pharmaceuticals in the plant in vitro cultures: strategies, approaches, and limitations to achieving higher yield
Tasiu Isah, Shahid Umar, Abdul Mujib, Maheshwar Sharma, P. Rajasekharan, Nadia Zafar, Arajmand Frukh
Plant Cell, Tissue and Organ Culture (PCTOC)
 
28.
The potent therapeutic effect of novel cyanobacterial isolates against oxidative stress damage in redox rats
O.A.M. Badr, I.I.S. EL‐Shawaf, H.A.S. El‐Garhy, M.M.A. Moustafa, O.A. Ahmed‐Farid
Journal of Applied Microbiology
 
29.
Elicitor Mixtures Significantly Increase Bioactive Compounds, Antioxidant Activity, and Quality Parameters in Sweet Bell Pepper
Lina Garcia-Mier, Sandra Jimenez-Garcia, Ramon Guevara-González, Ana Feregrino-Perez, Luis Contreras-Medina, Irineo Torres-Pacheco
Journal of Chemistry
 
30.
Utilisation of Bioactive Compounds from Agricultural and Food Waste
Antonietta Baiano
 
31.
Nutritional Composition and Antioxidant Properties of Fruits and Vegetables
Francisca Hernández-García, Ángel Carbonell-Barrachina
 
32.
Therapeutic Application of Betalains: A Review
Elaheh Madadi, Sahand Mazloum-Ravasan, Jae Yu, Ji Ha, Hamed Hamishehkar, Ki Kim
Plants
 
33.
Essential Oil and Hydrosol Extract Chemical Composition, Phytochemicals of Algerian Rhus pentaphylla Desf. and its Antioxidant Activity
Nassima Benmansour, Asma Allal, Chaouki Selles, Boufeldja Tabti, Alain Muselli
Current Bioactive Compounds
 
34.
Bioactive Natural Products
Semih Otles, Vasfiye Özyurt
 
35.
Molecular and metabolomic interventions for identifying potential bioactive molecules to mitigate diseases and their impacts on crop plants
Pooja Choudhary, Pooja Aggarwal, Sumi Rana, Radhakrishnan Nagarathnam, Mehanathan Muthamilarasan
Physiological and Molecular Plant Pathology
 
36.
Bioconversion of Callus-Produced Precursors to Silymarin Derivatives in Silybum marianum Leaves for the Production of Bioactive Compounds
Dina Gad, Hamed El-Shora, Daniele Fraternale, Elisa Maricchiolo, Andrea Pompa, Karl-Josef Dietz
International Journal of Molecular Sciences
 
37.
Strategies to Modulate Specialized Metabolism in Mediterranean Crops: From Molecular Aspects to Field
Raffaella Balestrini, Cecilia Brunetti, Maria Cammareri, Sofia Caretto, Valeria Cavallaro, Eleonora Cominelli, Palma De, Teresa Docimo, Giovanna Giovinazzo, Silvana Grandillo, Franca Locatelli, Erica Lumini, Dario Paolo, Cristina Patanè, Francesca Sparvoli, Marina Tucci, Elisa Zampieri
International Journal of Molecular Sciences
 
38.
Transcriptomic Analyses Shed Light on Critical Genes Associated with Bibenzyl Biosynthesis in Dendrobium officinale
Oluwaniyi Adejobi, Ju Guan, Liu Yang, Jiang-Miao Hu, Anmin Yu, Sammy Muraguri, Aizhong Liu
Plants
 
39.
Traceability of tomatoes (Solanun lycopersicum) based on their enzymatic profile
Marcy Rodrigues, Carolina Collazzo, Carolina Marques, Caroline Senna, Taiana Souza, Eliana Badiale-Furlong
Food Bioscience
 
40.
Edible Plant Sprouts: Health Benefits, Trends, and Opportunities for Novel Exploration
Simon Aloo, Fred Ofosu, Sheila Kilonzi, Umair Shabbir, Deog Oh
Nutrients
 
41.
Inhibition of multiple SARS-CoV-2 proteins by an antiviral biomolecule, seselin from Aegle marmelos deciphered using molecular docking analysis
Ramanathan Nivetha, Sreeramulu Bhuvaragavan, Kumar Muthu, Karuppasamy Ramanathan, Sundaram Janarthanan
Journal of Biomolecular Structure and Dynamics
 
42.
Transcriptomic and Metabolomic Analyses Reveals That Exogenous Methyl Jasmonate Regulates Galanthamine Biosynthesis in Lycoris longituba Seedlings
Qingzhu Li, Junxu Xu, Yuhong Zheng, Yongchun Zhang, Youming Cai
Frontiers in Plant Science
 
43.
Copper oxide (CuO) and manganese oxide (MnO) nanoparticles induced biomass accumulation, antioxidants biosynthesis and abiotic elicitation of bioactive compounds in callus cultures of Ocimum basilicum (Thai basil)
Saher Nazir, Hasnain Jan, Gouhar Zaman, Taimoor Khan, Hajra Ashraf, Bisma Meer, Muhammad Zia, Samantha Drouet, Christophe Hano, Bilal Abbasi
Artificial Cells, Nanomedicine, and Biotechnology
 
44.
Terpenoid evidences within three selected bryophyte species under salt stress as inferred by histochemical analyses
Marija Ćosić, Dušica Janošević, Mariana Oaldje, Milorad Vujićić, Ingeborg Lang, Marko Sabovljević, Aneta Sabovljević
Flora
 
45.
Moringa oleifera Leaf Extract Enhanced Growth, Yield, and Silybin Content While Mitigating Salt-Induced Adverse Effects on the Growth of Silybum marianum
Yun-Kiam Yap, Fadia El-Sherif, Eman Habib, Salah Khattab
Agronomy
 
46.
Multistep synthesis and screening of heterocyclic tetrads containing furan, pyrazoline, thiazole and triazole (or oxadiazole) as antimicrobial and anticancer agents
Chandrashekar Munikrishnappa, Kumar Suresh, Richie Bhandare, Sathish Konidala, Dilep Sigalapalli, Yogesh Vaishnav, Sampath Chinnam, Haya Yasin, Ahmed Al-karmalawy, Afzal Shaik
Journal of Saudi Chemical Society
 
47.
Application of Quality by Design Approach to the Pharmaceutical Development of Anticancer Crude Extracts of Crocus sativus Perianth
Olha Mykhailenko, Liudas Ivanauskas, Ivan Bezruk, Vilma Petrikaitė, Victoriya Georgiyants
Scientia Pharmaceutica
 
48.
Enhancing biosynthesis and bioactivity of Trachyspermum ammi seed essential oil in response to drought and Azotobacter chroococcum stimulation
Maryamolsadat Hashemi, Bita Behboodian, Ehsan Karimi, Ehsan Oskoueian
Chemical and Biological Technologies in Agriculture
 
49.
Modulated Light Dependence of Growth, Flowering, and the Accumulation of Secondary Metabolites in Chilli
Eva Darko, Kamirán Hamow, Tihana Marček, Mihály Dernovics, Mohamed Ahres, Gábor Galiba
Frontiers in Plant Science
 
50.
Repurposing Drugs as Novel Triple-negative Breast Cancer Therapeutics
Amiya Das, Pallavi Agarwal, Gaurav Jain, Geeta Aggarwal, Viney Lather, Deepti Pandita
Anti-Cancer Agents in Medicinal Chemistry
 
51.
GC-MS Analysis of Bioactive Compounds in Methanolic Extracts of Papaver decaisnei and Determination of Its Antioxidants and Anticancer Activities
Ahmed Jabbar, Fuad Abdullah, Kamaran Abdulrahman, Yaseen Galali, Abdullah Sardar, Christophe Hano
Journal of Food Quality
 
52.
Bioactive compounds from Taraxacum officinale extracts obtained by optimized ultrasound-assisted extraction
Marina Stanković, Dejan Arsenijević, Nevena Planojević, Jelena Terzić, Olgica Stefanović
Kragujevac Journal of Science
 
eISSN:2083-6007
ISSN:1230-0322