EFFECT OF SODIUM NITRATE (V) ON SACCHAROMYCES CEREVISIAE STRAINS OF DIFFERENT ANTIOXIDATIVE STATUS AND ENERGETIC METABOLISM
 
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Pol. J. Food Nutr. Sci. 2008;58(1):41–44
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ABSTRACT
The Saccharomyces cerevisiae yeast, differing with respect to the efficiency of antioxidating system and activity of mitochondrial processes, was used in the experiment. Sensitivity of these cells to 40-min incubation with sodium nitrate (V) was determined. Respiratory-competent cells deprived of the main antioxidating enzymes and the cells subjected to oxidative stress generated by antimycin A showed a greater sensitivity to sodium nitrate (V) than the cells deprived of functional mitochondria or the cells taken during the stationary phase of growth. The obtained results show that reactive oxygen species do not play an important part in the mechanisms of toxicity induced by the presence of sodium nitrates (V) in the case of cells with oxygen metabolism.
ISSN:1230-0322