The aim of the presented research was to determine the activity and interactions of the human intestinal microflora with biologically-active compounds as well as the degree of their in vitro survivability in the applied model of the gastrointestinal tract. Products (pasta) from green lentil seeds were obtained after thermoplastic treatment with the addition of plant extracts of garlic, onion and oregano (concentration of water extracts was 50 mg/mL). The highest antioxidative activity (32.43 mg Trolox/g) and content of phenolic compounds (3.21 mg/g) after the digestion process were determined for pasta from green lentil with the oregano extracts. Growth of the investigated bacteria (Enterobacteriaceae, Lactobacillus, Enterococcus, and Bifidobacterium genera) was affected by the digested noodles from green lentil with the plant extracts, especially in the case of the Enterococcus and Lactobacillus species. The bacterial count after digestion in the large intestine was maintained at a level of 10⁸ cfu/mL, whereas the noodles without the addition of plant extracts also stimulated microflora growth. As a result, the count of colonic bacteria was found to reach 10⁹-10¹⁰ cfu/mL.