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ORIGINAL ARTICLE
Antioxidant Activity of Extracts of Soursop (Annona muricata L.) Leaves, Fruit Pulps, Peels, and Seeds
1
Department of Food Technology, Vocational School of Technical Sciences, Tekirdağ Namik Kemal University, 59030 Tekirdağ, Turkey
2
Department of Chemistry, Faculty of Science and Arts, Namik Kemal University, 59030 Tekirdağ, Turkey
Submission date: 2019-07-24
Final revision date: 2019-09-24
Acceptance date: 2019-09-27
Online publication date: 2019-10-23
Publication date: 2019-11-18
Corresponding author
Hakime Hülya Orak
Department of Food Technology, Vocational School of Technical Sciences,, Tekirdağ Namik Kemal University, Namık Kemal Universitesi Teknik Bilimler MYO, 59030, SÜLEYMANPAŞA, Tekirdağ,, Turkey
Department of Food Technology, Vocational School of Technical Sciences,, Tekirdağ Namik Kemal University, Namık Kemal Universitesi Teknik Bilimler MYO, 59030, SÜLEYMANPAŞA, Tekirdağ,, Turkey
Pol. J. Food Nutr. Sci. 2019;69(4):359-366
KEYWORDS
TOPICS
ABSTRACT
The total phenolic content (TPC), total flavonoid content (TFC), and the antioxidant activity of soursop (Annona muricata L.) leaf, fruit pulp, seed, and peel extracts obtained using successive extraction with hexane (Hxn), dichloromethane (DCM), ethyl acetate (EtOAc), and methanol (MeOH) were determined. The Hxn soursop seed extract was analysed by GC-MS. The highest TPC was determined in MeOH extracts. MeOH and EtOAc extracts were rich sources of flavonoids. Generally, soursop leaf and fruit pulp extracts had the highest and the lowest both TPC and TFC, respectively. Fatty acids were dominant in the Hxn seed extract. Among antioxidants, terpenoids ((E)-nerolidolas as dominant) and phytosterols ((3-β)-stigmast-5-en-3-ol with high content) were identified. The soursop seed, followed by leaf and peel extracts (MeOH and EtOAc) had the highest DPPH• scavenging activity, TEAC, FRAP, and CUPRAC. Antioxidant activity of peel extracts (MeOH and EtOAc) was particularly high in β-carotene-linoleic acid emulsion system. Strong correlations were found between TPC, TFC, TEAC, FRAP, and results of DPPH assay. In conclusion, soursop leaves and fruit seeds and peels, which are cheap, waste plant material, could be considered as a source of phenolic antioxidants with a high antioxidant activity. Antioxidant activity of peel extracts (MeOH and EtOAc) was particularly high in β-carotene-linoleic acid emulsion system. The strong correlations between TPC, TFC, TEAC, FRAP and results of DPPH assay were found. In conclusion, soursop leaves and fruit seeds and peels, which are cheap, waste plant material, could be considered as a source of phenolic antioxidants with high antioxidant activity.
ACKNOWLEDGEMENTS
The authors would like to thank to Professor Dr. Adnan Orak for the statistical analyses. The authors would also like to thank Burhan Karaman from the Dominica Island for providing plant material.
FUNDING
This research did not get outsourcing.
REFERENCES (34)
1.
Aguilar-Hernandez, G., Garcia-Magana, M.L., Vivar-vera, M.A., Sayago-Ayerdi S.G., Sanchez-Burgos, J.A., Morales-Castro, J., Anaya-Esparza L.M., Gonzalez E.M. (2019). Optimisation of ultrasound-assisted extraction of phenolic compounds from Annona muricata by-products and pulp. Molecules, 24(5), art. no. 905.
2.
Apak, R., Güçlü, K., Özyürek, M., Karademir, S.E. (2004). Novel total antioxidant capacity index for dietary polyphenols and vitamin C and E, using their cupric ion reducing capability in the presence of neocuproine: CUPRAC method. Journal of Agricultural and Food Chemistry, 52(26), 7970–7981.
3.
Amarowicz, R., Pegg, R.B., Rahimi-Moghaddam, P., Barl B., Weil, J.L. (2004). Free-radical scavenging capacity and antioxidant activity of selected plant species from the Canadian prairies. Food Chemistry, 84(4), 551–562.
4.
Ayala-Zavala, J.F., Vega-Vega, V., Rosas-Domínguez, C., Palafox-Carlos, H., Villa-Rodriguez, J.A., Wasim Siddiqui, Md., Dávila-Aviña, J.E., González-Aguilar, G.A. (2011). Agro-industrial potential of exotic fruit byproducts as a source of food additives. Food Research International, 44(7), 1866–1874.
5.
Ayaz, M., Junaid, M., Ullah, F., Subhan, F., Sadiq, A., Ali, G., Ovais, M., Shahid, M., Ahmad, A., Wadood, A., El-Shazly, M., Ahmad, N., Ahmad, S. (2017). Anti-Alzheimer's studies on beta-sitosterol isolated from Polygonum hydropiper L. Frontiers in Pharmacology, 8, art. no. 697.
6.
Benites, R.S.R., Formagio, A.S.N., Argandoña, E.J.S., Volobuff, C.R.F., Trevizan, .N.F., Vieira, M.C., Silva, M.S. (2015). Contents of constituents and antioxidant activity of seed and pulp extracts of Annona coriacea and Annona sylvatica. Brazilian Journal of Biology, 75(3), 685–691.
7.
Benzie, I.F.F., Strain, J.J. (1996). The ferric reducing ability of plasma (FRAP) as a measure of ‘‘antioxidant power’’: the FRAP assay. Analytical Biochemistry, 239(1), 70–76.
8.
Brand-Williams, W., Cavalier, M.E, Berset, C. (1995). Use of free radical method to evaluate antioxidant activity. LWT - Food Science and Technology, 28(1), 25–30.
9.
Caboni, P., Ntalli, N.G., Aissani, N., Cavoski, I., Angioni, A. (2012). Nematicidal activity of (E,E)-2,4-decadienal and (E)-2-decenal from Ailanthus altissima against Meloidogyne javanica. Journal of Agricultural and Food Chemistry, 60(4), 1146–1151.
10.
Chamcheu, J.C., Rady, I., Chamcheu, R.N., Siddique, A.B., Bloch, M.B., Mbeumi, S.B., Babatunde, A.S., Uddin, M.B., Noubissi F.K., Jurutka, P.W., Liu Y.Y., Spiegelman, V.S., Whitfield, G.K., El Sayed,K.A. (2018). Graviola (Annona muricata) exerts anti-proliferative, anti clonogenic and pro-apoptotic effects in human non melanoma skin cancer UW-BCC1 and A431 cells in vitro: Involvement of hedgehog signaling. International Journal of Molecular Sciences, 19(6), art. no. 1791.
11.
Chan, W.K. Tan, L.T., Chan, K.G., Lee, L.H., Goh, B.H. (2016). Nerolidol: A sesquiterpene alcohol with multi-faceted pharmacological and biological activities. Molecules, 21(5), art. no. 529.
12.
Cheng, M.C., Lin, L.Y., Yu, T.H., Peng, R.Y. (2008). Hypolipidemic and antioxidant activity of mountain celery (Cryptotaenia japonica Hassk) seed essential oils. Journal of Agricultural and Food Chemistry, 56(11), 3997-4003.
13.
Coria-Téllez, A., Montalvo-Gonzalez, E., Yahia, E., Obledo-Vázquez, E. (2018). Annona muricata: a comprehensive review on its traditional medicinal uses, phytochemicals, pharmacological activities, mechanisms of action and toxicity. Arabian Journal of Chemistry, 11(5), 662–691.
14.
da Silva, L.M.R., de Figueiredo, E.A.T., Ricardo, N.M.P.S., Vieira, I.G.P., de Figueiredo, R.W., Brasil, I.M., Gomes, C.L. (2014). Quantification of bioactive compounds in pulps and by-products of tropical fruits from Brazil. Food Chemistry, 143, 398–404.
15.
da Silva, A.C., Jorge, N. (2017). Bioactive compounds of oils extracted from fruits seeds obtained from agroindustrial waste. European Journal of Lipid Science and Technology, 119(4), art. no. 1600024.
16.
Eromosele, C.O., Eromosele, I.C. (2002). Fatty acid compositions of seed oils of Haematostaphis barteri and Ximenia Americana. Bioresource Technology, 82(3), 303–304.
17.
George, V.C., Kumar, D.R.N., Suresh, P.K., Kumar, R.A. (2015). Antioxidant, DNA protective efficacy and HPLC analysis of Annona muricata (soursop) extracts. Journal of Food Science and Technology, 52(4), 2328–2335.
18.
Huang, W.Y., Cai, Y.Z., Corke, H., Su, M. (2010). Survey of antioxidant capacity and nutritional quality of selected edible and medicinal fruit plants in Hong Kong. Journal of Food Composition and Analysis, 23(6), SI, 510–517.
19.
Jiménez, V.M., Gruschwitz, M., Schweiggert, R.M., Carle, R., Esquivel, P. (2014). Identification of phenolic compounds in soursop (Annona muricata) pulp by high-performance liquid chromatography with diode array and electrospray ionization mass spectrometric detection. Food Research International, 65, SI, 42–46.
20.
Kosińska, A., Karamać, M., Estrella, I., Hernandez, T., Bartolome, B., Dykes, G.A. (2012). Phenolic compound profiles and antioxidant capacity of Persea americana Mill. peels and seeds of two varieties. Journal of Agricultural and Food Chemistry, 60(18), 4613–4619.
21.
Kuchtová, V. Kohajdová, Z., Karovičová, J., Lauková, M. (2018). Physical, textural and sensory properties of cookies incorporated with grape skin and seed preparations. Polish Journal of Food and Nutrition Sciences, 68(4), 309–317.
22.
Loizzo, M.R., Tundis, R., Bonesi, M., Menichini, F., Mastellone, V., Avallone, L., Menichini, F. (2012). Radical scavenging, antioxidant and metal chelating activities of Annona cherimola Mill. (cherimoya) peel and pulp in relation to their total phenolic and total flavonoid contents. Journal of Food Composition and Analysis, 25(2), 179–184.
23.
Marques, V., Farah, A. (2009). Chlorogenic acids and related compounds in medicinal plants and infusions. Food Chemistry, 113(4), 1370–1376.
24.
Miller, H.E. (1971). A simplified method for the evaluation of antioxidants. Journal of the American Oil Chemists' Society, 48, 91–91.
25.
Moghadamtousi, S.Z., Fadaeinasab, M., Nikzad, S., Mohan, G., Ali, H.M., Kadir, H.A. (2015). Annona muricata (Annonaceae): a review of its traditional uses, isolated acetogenins and biological activities. International Journal of Molecular Sciences, 16(7), 15625–15658.
26.
Moon, D.O., Kim, M.O., Choi, Y.H., Kim, G.Y. (2008). Beta-sitosterol induces G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways. Cancer Letters, 264(2), 181–191.
27.
Nam, J.S., Park, S.Y., Jang, H.L., Rhee, Y.H. (2017). Phenolic compounds in different parts of young Annona muricata cultivated in Korea and their antioxidant activity. Applied Biological Chemistry, 60(5), 535–543.
28.
Nawwar, M., Ayoub, N., Hussein, S., Hashim, A., El-Sharawy, R., Wende, K., Harms, M., Lindequist, U. (2012). A flavonol triglycoside and investigation of the antioxidant and cell stimulating activities of Annona muricata Linn. Archives of Pharmacal Research, 35(5), 761–767.
29.
Orak, H.H., Karamać, M., Amarowicz, R., Orak, A., Penkacik, K. (2019). Genotype-related differences in the phenolic compound profile and antioxidant activity of extracts from olive (Olea europaea L.) leaves. Molecules, 24(6), art. no. 1130.
30.
Oreopoulou, W., Tzia, C. (2007). Utilization of plant by-products for the recovery of proteins, dietary fibers, antioxidants, and colorants. In Oreopoulou, V. and Russ, W. (Eds.) Utilization of By-Products and Treatment of Waste in the Food Industry, Springer Science and Business Media, New York, USA, pp. 209–232.
31.
Pinto, L.C., de Souza, C.O., de Souza, S.A., da Silva, H.B., da Silva, R.R., Cerqueira-Lima, A.T., Teixeira, T.O., da Silva, T.M.S., Medeiros, K.C.P., Bittencourt, M., Brandão, H.R., Druzian, J.I., Conceição, A.S., Lopes, M.V., Figueiredo, C.A. (2018). Potential of Annona muricataL. seed oil: phytochemical and nutritional characterization associated with non-toxicity. Grasas Aceites, 69 (1), art. no. e234.
32.
Re, R., Pellegrini, N., Protrggente, A., Pannala, A., Yang, M., Rice-Evans, C. (1999). Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biology and Medicine, 26(9-10), 1231–1237.
33.
Sagar, N.A., Pareek, S., Sharma, S., Yahia, E.M., Lobo, M.G. (2018). Fruit and vegetable waste: Bioactive compounds, their extraction, and possible utilization. Comprehensive Reviews in Food Science and Food Safety, 17(3), 512–531.
34.
Zhishen, J., Mengcheng, T., Jianming, W. (1999). The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals. Food Chemistry, 64(4), 555–559.
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